Apr 062024
 

When I saw this article (and particularly when I learned something else I’ll get to after the article). I figured I had to go right to the top – Athena, the goddess of wisdom. Athena is likely so intellectual because she wasn’t born as we understand it – she emerged fully formed and an adult from Zeus’s head (I assume without the helmet, although the size of the helmet does suggest a large brain.)

At a time when we are aware that Alzheimer’s disease exists, and that there is no cure, many of us are terrified of it – of having it ourselves, and of it happening to someone near and dear. I know my mother was terrified of it. (She was spared it – she was still expertly solving crossword puzzles until her final coma, caused by pneumonia, at age 93.) So I can’t imagine anyone willing to miss out on any opportunity to avoid it, or to slow its progress.
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New studies suggest millions with mild cognitive impairment go undiagnosed, often until it’s too late

Mild cognitive impairment can be an early sign of Alzheimer’s disease or other dementias.
ivanastar/iStock via Getty Images Plus

Soeren Mattke, University of Southern California and Ying Liu, USC Dornsife College of Letters, Arts and Sciences

Mild cognitive impairment – an early stage of dementia – is widely underdiagnosed in people 65 and older. That is the key takeaway of two recent studies from our team.

In the first study, we used Medicare data for about 40 million beneficiaries age 65 and older from 2015 to 2019 to estimate the prevalence of mild cognitive impairment in that population and to identify what proportion of them had actually been diagnosed.

Our finding was sobering: A mere 8% of the number of cases with mild cognitive impairment that we expected based on a statistical model had actually been diagnosed. Scaled up to the general population 65 and older, this means that approximately 7.4 million cases across the country remain undiagnosed.

In the second study, we analyzed data for 226,756 primary care clinicians and found that over 99% of them underdiagnosed mild cognitive impairment in this population.

Why it matters

Mild cognitive impairment is an early symptom of Alzheimer’s disease in about half of cases and progresses to dementia at a rate of 10% to 15% per year. It includes symptoms such as losing the ability to remember recent events and appointments, make sound decisions and master complex tasks. Failure to detect it might deprive patients of an opportunity to get treated and to slow down disease progression.

Mild cognitive impairment can sometimes be caused by easily addressable factors, such as medication side effects, thyroid dysfunction or vitamin B12 deficiency. Since mild cognitive impairment has the same risk factors as cardiovascular disease, such as high blood pressure and cholesterol, medication management of these risks combined with diet and exercise can reduce the risk of progression.

In 2023, the Food and Drug Administration approved the drug lecanemab as the first disease-modifying treatment for Alzheimer’s disease, the most common cause of mild cognitive impairment. In contrast to previous drugs, which can temporarily improve symptoms of the disease, such as memory loss and agitation, this new treatment addresses the underlying cause of the disease.

Lecanemab, a monoclonal antibody, reduces amyloid plaques in the brain, which are toxic protein clumps that are believed to contribute to the progression of the disease. In a large clinical trial, lecanemab was able to reduce the progression of early-stage Alzheimer’s disease. A similar drug, donanemab, also succeeded in a clinical trial and is expected to be approved sometime in 2024.

However, these drugs must be used in the early stages of Alzheimer’s disease, ideally when a patient has only mild cognitive impairment, as there is no evidence that they are effective in advanced stages.

An earlier diagnosis leads to early treatment and better outcomes.

What still isn’t known

Many factors contribute to the lack of timely detection. But researchers don’t have a good understanding of the relative importance of those individual factors or how to reduce the high rate of underdiagnosis.

While distinct, symptoms are subtle and their slow progression means that they can be overlooked or misinterpreted as normal aging. A neurologist in China told our research team that diagnosis rates spike in China after the New Year’s holiday, when children who haven’t seen their parents for a year notice changes that are harder to pick up when interacting with someone daily.

Doctors also commonly discount memory concerns as normal aging and doubt that much can be done about it. While cognitive tests to distinguish mild cognitive impairment from pathologic decline do exist, they take about 15 minutes, which can be hard to come by during the limited time of a doctor’s visit and may require a follow-up appointment.

What’s next

People, particularly those in their 60s and beyond, as well as their families and friends need to be vigilant about cognitive decline, bring it up during doctor’s appointments and insist on a formal assessment.

The Medicare yearly “wellness” visit is an opportunity to explore such concerns, but only about half of beneficiaries take advantage of it.

Just as physicians ask patients about unexplained weight loss and take those concerns seriously, we believe questions that explore a patient’s cognitive state need to become the norm.

The Research Brief is a short take on interesting academic work.The Conversation

Soeren Mattke, Director of the USC Dornsife Brain Health Observatory, University of Southern California and Ying Liu, Research Scientist, Center for Economic and Social Research, USC Dornsife College of Letters, Arts and Sciences

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Pat B, (who is celebrating her fiftieth wedding anniversary today) has graciously given me permission to share that this coming Friday she has an appointment with her Doctor to discuss her memory loss. While no one can prove it, I would not be surprised to learn this was inspired by Athena. I can’t imagine anything wiser than getting checked out for any possible signs of dementia, knowing that waiting will not make it any better but it could make it worse. Thank you, Athena, and may you inspire all of us who are 65 or older to be wise also.

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Feb 062024
 

Joyce Vance thought this was important enough for an extra dedicated column and email … and I can’t disagree.

Judge Engoron’s Email

Joyce’s column includes a fair-sized photo of the actual email, which is almost as telling in tone as it is in fact.  I’m not sure that anyone other than a trial lawyer would have seen this coming, but, on the other hand, it makes a lot of sense, including the part about who is legally entitled to what information about whom, which would certainly not have occurred to me.  I was aware of “falsus in uno, falsus in omnibus” but it hadn’t occurred to me that anyone would think to use Weisselberg as a defense witness.  As Hercule Poirot would have said (and did say, many times) – it gives one furiously to think.

Fasten your seat belts, it’s going to be a bumpy ride.

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Everyday Erinyes #340

 Posted by at 12:08 pm  Plus, Politics
Oct 162022
 

Experts in autocracies have pointed out that it is, unfortunately, easy to slip into normalizing the tyrant, hence it is important to hang on to outrage. These incidents which seem to call for the efforts of the Greek Furies (Erinyes) to come and deal with them will, I hope, help with that. As a reminder, though no one really knows how many there were supposed to be, the three names we have are Alecto, Megaera, and Tisiphone. These roughly translate as “unceasing,” “grudging,” and “vengeful destruction.”

This is the culture article I had hoped to do last week, but it’s really timeless. I’d like to start with a personal story. Back in the oughts, when I was working at AAA, and our cubicles had low walls so we could see and possibly talk to people across to us, one day the woman across from mee said something, I forget exactly what, but with which I heartily agreed. I had seen a joke that morning which put me in mind of a particular phrase and I responded “For shizzle!” She was startled and said, “I didn’t even think you would know who Diddy was.” I said, “Well, yeah, I listen to classical music pretty well all the time, but that doesn’t mean I have to be ignorant.” And she replied that most people don’t think that way. And that little conversation was what led to our becoming BFFs. And I have learned so much and gotten so much joy from our friendship, and I think she has too, that I am so grateful to have, and so determined to continue having, an open mind.

However, I’m afraid she was right – most people don’t think that way. I can’t forget all the heads that exploded when Mr. Robert Zimmerman received the Nobel for Literature one year. Or that when the musical “Of Thee I Sing” received a Pulitzer and every creative talent who worked on it received the award except George Gershwin – that was not in my lifetime, but it’s such a well-known event, and so ironic, it sticks with me. And then, there’s “The Lexicon of Musical Invective,” a collection of quotes from history in which older composers, and some critics, verbally destroyed younger composers who turned out to be as great as or greater than their critics. You wouldn’t believe, for instance, the trash talk about Beethoven.

So when I saw this article about how one creative activity can spill over into, and even foster, a different creative activity that is unexpected, I wanted to share it. You don’t need to agree with me or the author – you don’t even need to read it – but it’s natural for me to want to share something – a type of openness – which has given so much to me.
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Kanye may not like books, but hip-hop fosters a love of literature

Kanye West provoked criticism recently when he compared reading to eating Brussels sprouts.
Gotham via Getty Images

A.D. Carson, University of Virginia

When Ye – the artist formerly known as Kanye West – stated during a recent podcast that he doesn’t read books, some people questioned whether he was sending the wrong message to children.

Those questions took on more importance in light of the fact that Ye recently launched Donda Academy, a private educational venture named after his late mother, Donda West, who was herself an English professor.

As a rap artist, author and academic, I would never argue that reading lots of books is the only path to gaining knowledge or showing intelligence.

After all, I created the first-ever peer-reviewed hip-hop album published by a university press. For my doctoral dissertation in 2017, I made a rap album and resisted any calls to submit a formally written explanation of the work.

Verbal intelligence

Even as a former high school literature teacher, I never believed the only way – or even the primary way – for people to demonstrate intellect was through reading books. I think that performing a freestyle – that is to say, writing and reciting seemingly spontaneous rap lyrics on the spot – requires levels of intelligence that are often overlooked or racistly cast off as “natural talent” that don’t require studying or practice. For instance, the mind-blowing 10-minute freestyle that rapper Black Thought performed live on New York radio station Hot 97 in 2017 is a master-class demonstration of brilliance that is a result of years of study and practice.

Black Thought performs a 10-minute freestyle on New York radio station Hot 97 in 2017.

In some ways, you might say Kanye West and I are on the same page. Where I disagree with Ye, however, is in his total dismissal of reading books, which he likens to “eating Brussels sprouts.” Rap music is a lot of things, but it includes quite a bit of reverence for literature.

A direct rap response to Kanye West’s dismissive remarks about not reading books, 10 years in advance: “A.R.T. [The Motto],” by A.D. Carson.

Kanye as ‘Gatsby’

Books have a high place in hip-hop. As I’ve pointed out in the various book chapters that I’ve authored on different aspects of rap music – and in the classes that I teach – a wealth of lyrics that contain direct and indirect references to a rich array of literary works. These works span multiple millennia and originate from across the globe.

And long before the book-hating controversy, I once referred to Ye as potentially being hip-hop’s Jay Gatsby, a reference to the central character of F. Scott Fitzgerald’s 1925 novel “The Great Gatsby,” because of the striking parallels that I saw between their lives. The novel contains teachable comparisons to “Graduation” in its use of the flashing-lights metaphor for hope and desire for wealth and class.

While Kanye West professes a disdain for books, the same cannot be said of many of his predecessors and contemporaries.

For instance, in 1996, Tupac Shakur released his 1996 album “The Don Killuminati: The 7 Day Theory” under the alias Makaveli – a variation of the name of author Niccolò Machiavelli. Machiavelli’s 16th-century works “The Prince” and “Discourses on Livy” could offer interesting insights into the album and the creative process that Tupac undertook during the final period of his life. For example, Machiavelli famously details his observations on obtaining and keeping political power in “The Prince.” Similarly, Tupac ends his album by talking about his own ascendancy of sorts, shouting out “soldiers with military minds” and detailing foretold rules of war.

What follows is a brief overview of other notable instances in which rap artists refer – either directly or indirectly – to influential literary works written by authors from around the world and throughout the ages.

Black Star’s 1998 ‘Thieves in the Night’

This song name-drops and quotes Toni Morrison’s “The Bluest Eye.” The hook of the song borrows and revises the quote from the novel:

A book cover emblazoned with the words 'The Bluest Eye: A Novel by Toni Morrison'
Toni Morrison’s novel ‘The Bluest Eye.’
Penguin Random House

“… for we were not strong, only aggressive; we were not free, merely licensed; we were not compassionate, we were polite; not good, but well behaved. We courted death in order to call ourselves brave, and hid like thieves from life.”

Noname’s 2021 single ‘Rainforest’

This song directly names the 1961 book “The Wretched of the Earth” by psychiatrist and political philosopher Frantz Fanon. It is a lyrical allusion to the ongoing effects of colonialism.

“Rainforest” by Noname.

KXNG Crooked and Joell Ortiz’s 2022 song ‘Heat Wave’

Crooked makes a passing reference in this song to Plato’s philosophical text “Symposium,” in which characters, including the philosopher Socrates, compete performing improvised speeches. Plato isn’t exactly writing about rap battles, but there are similarities.

“Heat Wave” by KXNG Crooked and Joell Ortiz.

Kendrick Lamar’s 2015 album ‘To Pimp a Butterfly’

There are interesting parallels to Ralph Ellison’s “Invisible Man” throughout the album. The insistent reference to “yams” on the song “King Kunta” evokes the scene from the 1952 novel in which the narrator encounters a vendor selling yams, which remind him of home, so he eats them until they make him sick.

“King Kunta” by Kendrick Lamar.

The Roots’ 2004 album ‘The Tipping Point’

This album borrows its name from a 2000 Malcolm Gladwell book. Gladwell describes a tipping point as “the moment of critical mass, the threshold, the boiling point.” The album cover features a photo of a young Malcolm X, presumably at a tipping point of sorts, before he becomes a world-famous Muslim minister and eventually co-authors the influential 1965 “The Autobiography of Malcolm X as told to Alex Haley.”

“The Tipping Point” by The Roots.

Common’s 2000 album ‘Like Water for Chocolate’

Book cover of 'Assata: An Autobiography,' by Assata Shakur.
‘Assata: An Autobiography,’ by Assata Shakur.
Biblio

This album takes its name from the 1989 novel by Mexican author Laura Esquivel. The book uses magical realism to convey the emotions of the main character, Tita, to the people who eat the food she makes while being a caretaker for her mother, which prevents her from fulfilling her true desires.

The album also features a song called “A Song for Assata” that features audio from an interview Common did with exiled Black freedom fighter Assata Shakur, author of the 1989 book “Assata: An Autobiography.”

Dead prez’s 2000 album ‘Let’s Get Free’

This album features many literary illusions and influences. Notably, the lyrics of the song “We Want Freedom” begin with the words, “I Ching,” which is the name of an ancient Chinese text. The group’s logo comprises a symbol, hexagram 46, used in the text that represents the word “army.” Group member stic.man says the symbol is meant to represent “forward motion, progress and adapting in our lives.”

“We Want Freedom” by dead prez.

Rapsody’s 2019 album ‘Eve’

All the titles of the songs on this album are the names of noteworthy women. “Eve” is the first woman named in a major work of literature – the Bible – and several of the other women mentioned are authors, including “Oprah,” “Myrlie,” “Michelle” and “Maya.” The song named for Maya Angelou focuses on themes in Angelou’s work and also quotes from her writing.

“Maya” by Rapsody.

Perhaps Kanye West’s recent remarks about reading will inspire some thoughtful conversation about how American society views reading and determines intelligence. If they do, the archives of hip-hop – whether in book form or music – offer an abundance of ways to take those conversations to greater depths.The Conversation

A.D. Carson, Assistant Professor of Hip-Hop, University of Virginia

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Alecto, Megaera, and Tisiphone, we don’t all need to be alike – in fact, we shouldn’t. But paying attention – and respect – to things that others care about, and the roles those things play in their lives, can open us up to a world of wonder we didn’t know existed. Help us to do that, in ways that work for us, as best we can.

The Furies and I will be back.

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Everyday Erinyes #338

 Posted by at 4:38 pm  Plus, Politics
Oct 022022
 

Experts in autocracies have pointed out that it is, unfortunately, easy to slip into normalizing the tyrant, hence it is important to hang on to outrage. These incidents which seem to call for the efforts of the Greek Furies (Erinyes) to come and deal with them will, I hope, help with that. As a reminder, though no one really knows how many there were supposed to be, the three names we have are Alecto, Megaera, and Tisiphone. These roughly translate as “unceasing,” “grudging,” and “vengeful destruction.”

I’m not sure when “denial”came to be used to describe a condition, rather than just something a normal person did when falely accused, or a liar did when accurately accused. The first time I was aware of the word in the state-of-mind meaning was from the works of Elisabeth Kubler-Ross; I don’t even remember whether that was directly or indirectly. Now, that seems to pretty much all it means – a stage one passes through while grieving, or the state of belief of an addict that he or she can “take it or leave it,” but always something which is – not exactly involuntary, but not deliberate.

Jared Del Rosso, though he may not be the King of Denial, is here to point out that there are still times when it is very deliberate, and when so exercised, can affect – infect – other people – sometimes one or two, sometimes thousands or millions. What I thought of as the original meaning of denial may not be in common usage any more, but it is still in common use, every day, to whitewash the people who are doing it.
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How to get away with torture, insurrection, you name it: The techniques of denial and distraction that politicians use to manage scandal

An image of a mock gallows on the grounds of the Capitol on Jan. 6, 2021, is shown during a House committee hearing.
AP Photo/J. Scott Applewhite

Jared Del Rosso, University of Denver

The U.S. House select committee investigating the Jan. 6, 2021 insurrection intends to hold another public hearing, likely the last before it releases its official report. The hearing had been scheduled for Sept. 28, 2022 but was postponed because of Hurricane Ian.

Through earlier hearings this past summer, the committee has shown how former President Donald Trump and close associates spread the “big lie” of a stolen election. The hearings have also shown how Trump stoked the rage of protesters who marched to the U.S. Capitol and then refused to act when they breached the building.

The hearings have aired in prime time and dominated news cycles. Still, polling conducted in August by Monmouth University found that around 3 in 10 Americans still believe that Trump “did nothing wrong regarding January 6.”

As a sociologist who studies denial, I analyze how people ignore clear truths and use rhetoric to convince others to deny them, too. Politicians and their media allies have long used this rhetoric to manage scandals. Trump and his supporters’ responses to the Jan. 6 investigation are no exception.

Stages of denial

Commonly, people think of denial as a state of being: Someone is “in denial” when they reject obvious truths. However, denial also consists of linguistic strategies that people use to downplay their misconduct and avoid responsibility for it.

These strategies are remarkably adaptable. They’ve been used by both political parties to manage wildly different scandals. Even so, the strategies tend to be used in fairly predictable ways. Because of this, we can often see scandals unfold through clear stages of denial.

In my previous research on denial and U.S. torture, I analyzed how the George W. Bush administration and supporters in Congress adjusted the forms of denial they used as new allegations and evidence of abuses in the global “war on terror” became public.

For instance, after photographs of torture at the Abu Ghraib prison in Iraq were released in the spring of 2004, Abu Ghraib was described as a deplorable but isolated incident. At the time, there wasn’t serious public evidence of detainee abuse at other U.S. facilities.

Later revelations about the use of torture at Guantánamo Bay and secret CIA black sites changed things. The Bush administration could no longer claim that torture was an isolated incident. Officials also faced allegations that they had directly and knowingly authorized torture.

A museum display shows a wooden board the size of a person below the words 'What is torture?'
An exhibit on torture includes a section on waterboarding in the International Spy Museum in Washington in 2019.
AP Photo/Jacquelyn Martin

Facing these allegations, Bush and his supporters began justifying and downplaying torture. To many Americans, torture, once deplorable, was rebranded as an acceptable national security tool: “enhanced interrogation.”

As the debate about torture shows, political responses to scandal often begin with outright denials. But rarely do they end there. When politicians face credible evidence of political misconduct, they often try other forms of denial. Instead of saying allegations are untrue, they may downplay the seriousness of allegations, justify their behavior or try to distract from it.

It’s not just Republican administrations that use denial in this way. When the Obama administration could no longer outright deny civilian casualties caused by drone strikes, it downplayed them. In a 2013 national security speech, President Barack Obama contrasted drone strikes with the use of “conventional air power or missiles,” which he described as “far less precise.” He also justified drone strikes, arguing that “to do nothing in the face of terrorist networks would invite far more civilian casualties.”

Scandal strategies in play

Americans watched the Jan. 6 insurrection on TV and social media as it happened. Given the vividness of the day, outright denials of the insurrection are particularly far-fetched and marginal – though they do exist. For example, some Trump supporters have claimed that left-wing “antifa” groups breached the Capitol – a claim many rioters themselves have rejected.

Some of Trump’s supporters in Congress and the media have repeated the claim that the insurrection was staged to discredit Trump. But given Trump’s own vocal support for the insurrectionists, supporters usually deploy more nuanced denials to downplay the day’s events.

So what happens when outright denial fails? From ordinary citizens to political elites, people often respond to allegations by “condemning the condemners,” accusing their accusers of exaggerating – or of doing worse things themselves, a strategy called “advantageous comparisons.”

Together, these two strategies paint those making accusations as untrustworthy or hypocritical. As I show in my new book on denial , these are standard denials of those managing scandals.

“Condemning the condemners” and “advantageous comparisons” have been central to efforts to minimize the Jan. 6 insurrection, as well. Some critics of the committee downplay the insurrection by likening it to the Black Lives Matter protests, despite the fact that the vast majority were peaceful.

“For months, our cities burned, police stations burned, our businesses were shattered. And they said nothing. Or they cheer-led for it. And they fund-raised for it. And they allowed it to happen in the greatest country in the world,” Republican Rep. Matt Gaetz said during Trump’s second impeachment. “Now, some have cited the metaphor that the president lit the flames. Well, they lit actual flames, actual fires!”

Similar comparisons reappeared amid the House select committee’s hearings. One NFL coach called Jan. 6 a “dust-up” by comparison to the Black Lives Matter protests.

These forms of denial do several things at once. They direct attention away from the original focus of the scandal. They minimize Trump’s role in inciting the violence of Jan. 6 by making the claim that Democrats incite even more destructive forms of violence. And they discredit the investigation by suggesting that those leading it are hypocrites, more interested in scoring political points than in curtailing political violence.

A small group of protesters in a circle, with a man holding a 'Trump won' poster in the middle.
Trump supporters and members of the far-right group Proud Boys gather during a ‘Justice for January 6th Vigil’ in New York on Jan. 6, 2022.
AP Photo/Yuki Iwamura

Trickle-down denial

These denials may not sway a majority of Americans. Still, they’re consequential. Denial trickles down by providing ordinary citizens with scripts for talking about political scandals. Denials also reaffirm beliefs, allowing people to filter out information that contradicts what they hold to be true. Indeed, ordinary Americans have adapted “advantageous comparisons” to justify the insurrection.

This has happened before. For example, in a study of politically active Americans, sociologists Barbara Sutton and Kari Marie Norgaard found that some Americans adopted pro-torture politicians’ rhetoric – such as supporting “enhanced interrogation” and defending practices like waterboarding as a way to gather intelligence, even as they condemned “torture.”

For this reason, it’s important to recognize when politicians and the media draw from the denial’s playbook. By doing so, observers can better distinguish between genuine political disagreements and the predictable denials, which protect the most powerful by excusing their misconduct.

Article updated to indicate that the House select committee hearing scheduled for Sept. 28, 2022 was postponed on Sept. 27, 2022.The Conversation

Jared Del Rosso, Associate Professor of Sociology and Criminology, University of Denver

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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AMT, as if it wasn’t already hard enough to determine where truth is. Although Del Rosso’s work may actually make it easier. Certainly he shows that no individual and no group is immune from it. That’s a hard truth but it’s a good one to be aware of if one wants to know the truth.

The Furies and I will be back.

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Everyday Erinyes #320

 Posted by at 5:56 pm  Plus, Politics
May 292022
 

Experts in autocracies have pointed out that it is, unfortunately, easy to slip into normalizing the tyrant, hence it is important to hang on to outrage. These incidents which seem to call for the efforts of the Greek Furies (Erinyes) to come and deal with them will, I hope, help with that. As a reminder, though no one really knows how many there were supposed to be, the three names we have are Alecto, Megaera, and Tisiphone. These roughly translate as “unceasing,” “grudging,” and “vengeful destruction.”

There are a lot of things I could be putting front and center this week. However, they are pretty well already front and center. This story got knocked off of all the front pages, and I thought, before it gets back on them, it might be good to have some common sense and facts So here it is.
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What is monkeypox? A microbiologist explains what’s known about this smallpox cousin

Monkeypox causes lesions that resemble pus-filled blisters, which eventually scab over.
CDC/Getty Images

Rodney E. Rohde, Texas State University

On May 18, 2022, Massachusetts health officials and the Centers for Disease Control and Prevention confirmed a single case of monkeypox in a patient who had recently traveled to Canada. Cases have also been reported in the United Kingdom and Europe.

Monkeypox isn’t a new disease. The first confirmed human case was in 1970, when the virus was isolated from a child suspected of having smallpox in the Democratic Republic of Congo (DRC). Monkeypox is unlikely to cause another pandemic, but with COVID-19 top of mind, fear of another major outbreak is understandable. Though rare and usually mild, monkeypox can still potentially cause severe illness. Health officials are concerned that more cases will arise with increased travel.

I’m a researcher who has worked in public health and medical laboratories for over three decades, especially in the realm of diseases with animal origins. What exactly is happening in the current outbreak, and what does history tell us about monkeypox?

A cousin of smallpox

Monkeypox is caused by the monkeypox virus, which belongs to a subset of the Poxviridae family of viruses called Orthopoxvirus. This subset includes the smallpox, vaccinia and cowpox viruses. While an animal reservoir for monkeypox virus is unknown, African rodents are suspected to play a part in transmission. The monkeypox virus has only been isolated twice from an animal in nature. Diagnostic testing for monkeypox is currently only available at Laboratory Response Network labs in the U.S. and globally.

The name “monkeypox” comes from the first documented cases of the illness in animals in 1958, when two outbreaks occurred in monkeys kept for research. However, the virus did not jump from monkeys to humans, nor are monkeys major carriers of the disease.

Electron microscope view of monkeypox, showing oval-shaped, mature virus particles and spherical, immature virions
Monkeypox belongs to the Poxviridae family of viruses, which includes smallpox.
CDC/ Cynthia S. Goldsmith

Epidemiology

Since the first reported human case, monkeypox has been found in several other central and western African countries, with the majority of infections in the DRC. Cases outside of Africa have been linked to international travel or imported animals, including in the U.S. and elsewhere.

The first reported cases of monkeypox in the U.S. was in 2003, from an outbreak in Texas linked to a shipment of animals from Ghana. There were also travel-associated cases in November and July 2021 in Maryland.

Because monkeypox is closely related to smallpox, the smallpox vaccine can provide protection against infection from both viruses. Since smallpox was officially eradicated, however, routine smallpox vaccinations for the U.S. general population were stopped in 1972. Because of this, monkeypox has been appearing increasingly in unvaccinated people.

Person getting temperature tested at airport
Indonesia began screening travelers after a monkeypox case was reported in Singapore in May 2019.
Jepayona Delita/Future Publishing via Getty Images

Transmission

The virus can be transmitted through contact with an infected person or animal or contaminated surfaces. Typically, the virus enters the body through broken skin, inhalation or the mucous membranes in the eyes, nose or mouth. Researchers believe that human-to-human transmission is mostly through inhalation of large respiratory droplets rather than direct contact with bodily fluids or indirect contact through clothes. Human-to-human transmission rates for monkeypox have been limited.

Health officials are worried the virus may currently be spreading undetected through community transmission, possibly through a new mechanism or route. Where and how infections are occurring are still under investigation.

Signs and symptoms

After the virus enters the body, it starts to replicate and spread through the body via the bloodstream. Symptoms usually don’t appear until one to two weeks after infection.

Monkeypox produces smallpox-like skin lesions, but symptoms are usually milder than those of smallpox. Flu-like symptoms are common initially, ranging from fever and headache to shortness of breath. One to 10 days later, a rash can appear on the extremities, head or torso that eventually turns into blisters filled with pus. Overall, symptoms usually last for two to four weeks, while skin lesions usually scab over in 14 to 21 days.

While monkeypox is rare and usually non-fatal, one version of the disease kills around 10% of infected people. The form of the virus currently circulating is thought to be milder, with a fatality rate of less than 1%.

Vaccines and treatments

Treatment for monkeypox is primarily focused on relieving symptoms. According to the CDC, no treatments are available to cure monkeypox infection.

Because smallpox is closely related to monkeypox, the smallpox vaccine can protect against both diseases.

Evidence suggests that the smallpox vaccine can help prevent monkeypox infections and decrease the severity of the symptoms. One vaccine known as Imvamune or Imvanex is licensed in the U.S. to prevent monkeypox and smallpox.

Vaccination after exposure to the virus may also help decrease chances of severe illness. The CDC currently recommends smallpox vaccination only in people who have been or are likely to be exposed to monkeypox. Immunocompromised people are at high risk.The Conversation

Rodney E. Rohde, Regents’ Professor of Clinical Laboratory Science, Texas State University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Alecto, Megaera, and Tisiphone, it sounds to me as though health officials are paranoid over this – and I say that not in mockery, but in approval. Unfounded assumptions, particularly about transmission, are one of the ways pandemics start and get worse.There’s quite a bit we don’t know about monkey pox – but with the professionals watching it as they are, that will likely change soon. Hopefully we will learn enough.

The Furies and I will be back.

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Mar 232022
 

Yesterday, my mail contained a jury summons. That’s the kind of mail that gets me off my fanny to go out to the mailbox, and of course I did. Now, I’ve seen this film before, so I know it doesn’t necessarily mean I’ll have to serve. Also, it isn’t until the end of April. So it’s cool. Also, I had a hard time finding things that were both interesting and not repetetive. There was a whole lot of repetition going on yesterday. I got to the point that if I had had to read one more story about a racist Republican Senator, I might have barfed. So I filled in with the Smithsonian, which is trivial, but at least different. (The Food for Thought is also just for fun.)

Cartoon

Short Takes –

The New Yorker – Radio Ukraine
Quote – The station staff has dispersed, with Bogdan Bolkhovetsky, the general manager, and Roman Davydov, the program director, holed up in a town in the Carpathians, keeping production moving over unreliable Internet and communicating with listeners by text. They don’t know how many of their broadcasting stations are still functioning, and their tower in Kyiv could be destroyed at any time. But “we are not doing anything heroic,” Bolkhovetsky told Nicolas Niarchos, who visited their makeshift studio. “We are still in a lot of luck, having what we have right now. Thousands of people were not so lucky as we are. . . . We’re just doing what we can under these unusual circumstances.”
Click through for David Remnicks podcast and/or even more articles on the war.

Smithsonian – Take the cherry blossom personality quiz to see which species speaks to you!
Quote – Six varieties of cherry blossom trees bloom in the Smithsonian Gardens, each with its own unique flowers and features.
Click through for the quiz. As usual, there are questions for which no answer is right for me, and it will probably be the same for you. But at least it’s fun looking at the pictures. (I came out as the “weeping” cherry tree.)

Women’s History – Wikipedia – Rosalind Franklin
Quote – Rosalind Elsie Franklin … was an English chemist and X-ray crystallographer whose work was central to the understanding of the molecular structures of DNA (deoxyribonucleic acid), RNA (ribonucleic acid), viruses, coal, and graphite. Although her works on coal and viruses were appreciated in her lifetime, her contributions to the discovery of the structure of DNA were largely unrecognized during her life, for which she has been variously referred to as the “wronged heroine”, the “dark lady of DNA”, the “forgotten heroine”, a “feminist icon”, and the “Sylvia Plath of molecular biology”.
Click through for bio. You may have heard of her. Watson and Crick could not have completed the DNA model without her work Women from prehistory and up to the end of the Middle Ages appear to have had less difficulty getting recgnized for their accomplishments, and lso more freedom to make them, than from the Industrial Revolution forward.

Food For Thought:

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Everyday Erinyes #300

 Posted by at 5:03 pm  Plus, Politics
Jan 092022
 

Experts in autocracies have pointed out that it is, unfortunately, easy to slip into normalizing the tyrant, hence it is important to hang on to outrage. These incidents which seem to call for the efforts of the Greek Furies (Erinyes) to come and deal with them will, I hope, help with that. As a reminder, though no one really knows how many there were supposed to be, the three names we have are Alecto, Megaera, and Tisiphone. These roughly translate as “unceasing,” “grudging,” and “vengeful destruction.”

Walter Shaub writes a newsletter for the Project on Government Oversight, called “The Bridge.” It is only published in emails – there is no link I can give you so you can find it and read it. If I want to share it in full, I have no choice except to reprint it in full. However, I have always thought, and now courts have held, that if you put something into an email it is fair gme to reprint.

Shaub is a specialist in ethics, and that is the focus of The Bridge. This week’s issue (like just about everything else on the ‘net this week) is related to last year’s insurrection, and he has thughts. Thoughts which I consider worth sharing.
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Today is the anniversary of the January 6, 2021, attack on the Capitol. Others will offer analyses of ongoing investigations into the attack. I want to reflect on its significance.

A DAY THAT HAS NOT LIVED IN INFAMY

Former president Donald Trump tried to overthrow American democracy from inside the government. Members of Congress and the vice president fled from a mob. People died. More were injured. The casualties include more than 140 police officers who defended the Capitol against an overwhelming onslaught. The republic was threatened.

You wouldn’t know it, though.

Insurrection sympathizers have celebrated their plot like the storming of the Bastille. Others have labeled it “America’s failed insurrection,” as though a verdict of failure were possible yet. The Department of Justice boasts that it has arrested 725 people, but they are low-level insurrectionists; the vast majority are charged with mere property crimes or obstruction of the investigation. There’s no public indication that DOJ is pursuing those who incited the attack. Even the name DOJ has given its prosecutorial effort downplays the significance of the insurrection: “Capitol Breach Cases.”

Capitol breach cases? The full name of the 9/11 Commission was “The National Commission on Terrorist Attacks Upon the United States.” By DOJ’s logic, it could’ve been called the “Unauthorized Flight Diversion Commission.” What happened on January 6 was a terrorist attack. Terrorists warrant more than bureaucratic language and slaps on the wrist.

Congress has shown more courage, but its powers are as limited as its capacity for rapid response. Congress took half a year to establish a committee to investigate the attack. News reports suggest the committee has uncovered a trove of information from hundreds of cooperating witnesses. But its initial report isn’t expected until this summer. Complicating the effort, some key witnesses have openly defied the committee and seem determined to stall in the hope of a leadership change in Congress next year.

There’s a reason accountability has been elusive: the movement behind the attack on the republic remains powerful. Just hours after the attack, 147 members of Congress voted to overturn the election because they didn’t like the result. Those who incited a mob to storm the Capitol lost a battle, not the war on democracy. The threat today is as real as it was then.

Seven Days in May

The persistence of the threat isn’t a cause for despair; it’s a call to action. Democracy has always been fragile, and threats to freedom are not new. The 1964 film Seven Days in May offers an instructive reminder of that. This black and white thriller was always a favorite of mine for its artful portrayal of the republic’s vulnerability and the need for vigilance. The film has never felt more relevant than it does now.

In the film, the chairman of the Joint Chiefs of Staff, General James Mattoon Scott, plots with other Pentagon leaders and at least one member of Congress to overthrow the government. The film opens with a protest outside the White House, where the treacherous general’s followers converge with followers of the president. Violence erupts.

Later, when General Scott delivers an inappropriately political speech at Madison Square Garden, it becomes clear that he has been priming the public for a change in leadership. His plot is conceived with military precision, and it fails only due to the intervention of a faithful marine, played by Kirk Douglas, who lives up to the Marine Corps’ motto: Semper Fidelis.

This depiction of democracy narrowly escaping destruction served as a warning about how those with authoritarian ambitions can misuse the government’s own machinery against itself. The fictional General Scott is said to be based partly on two real-life figures. One was the notorious General Edwin Walker, who resigned after being stripped of his command for extremist political activities and was later charged with insurrection for participating in a deadly riot to block Mississippi University’s integration. The other was General Curtis LeMay, who objected bitterly to President John F. Kennedy’s refusal to invade Cuba.

President Kennedy received an advance copy of the book on which the film was based and found it believable. The military’s top brass had earned his distrust by advocating for the tactical use of nuclear weapons and proposing terrorist attacks in Florida to generate support for invading Cuba. Kennedy urged Hollywood to make the book into a movie as a warning about the republic’s fragility.

The particulars of the film’s storyline differ from the events of January 6, but the particulars don’t matter; this is the story of a threat from within the government. In both cases, an attack incited by a demagogue follows a protest outside the White House. The film ends when the plot is foiled. We’re past that point with our insurrection, but Seven Days in May can still serve as a warning about what happens next. In the film, most (not all) of the conspirators are forced out of government, but political circumstances save them from more serious accountability for their treachery. In the absence of accountability, the viewer can’t escape feeling that the republic remains vulnerable. It could happen again.

The same is true now. President Trump and some of his allies are out of government, but they haven’t faced further accountability. Trump’s chief of staff, Mark Meadows, joined him in pressuring DOJ officials and Georgia state election officials to help overturn the election results. Trump used his public platform to incite the attack. His Pentagon appointees did not come to the aid of the hopelessly outnumbered police for hours. Trump and his supporters continue to lie about voter fraud and sow doubts about our election systems. It could happen again.

In the year since the attack on the Capitol, the danger to the republic has only grown. The movement has shifted tactics, focusing now on voter suppression and keeping its adherents primed for future action with lies about voter fraud. We should be pressing our leaders to hold those responsible for the insurrection accountable. We should be pressing them to pass voting rights legislation. We should be active participants in the work of democracy. We must be. The fate of the republic depends on it.

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Alecto, Megaera, and Tisiphone, The 1994 TV movie “The Enemy Within” was more or less billed as an updated remake of “Seven Days in May.” I don’t know how accurate that is, nor how good it is (it couldn’t have JFK’s seal of approval, for one thing), but it is available to stream, whereas I believe “Seven Days in May” would be DVD or BluRay (or of course one could read the book.) I’ve always maintaind that what people learn through storytelling is better learned and more deeply internalized than anything learned through any other method. So any of those possibilities may well be worth a shot.

The Furies and I will be back.

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Nov 272021
 

Let me make clear that I am not attempting to stand in for SoINeedAName – even if that were not impossible given his talents (yes, I have some of my own, but they are not in competition with his), the added responsibility is not something i am ready to take on.

However, I could not resist this headline:

Dancers meet rescue pets in Fort Collins ballet company’s annual ‘Muttcracker’ shoot

And when I read on, and saw the photos, I could resist even less.

Yes, Virginia. There is a Santa Claus, and he’s officially brought back the “Muttcracker” photo shoot as a new Fort Collins holiday tradition.

For the second year in a row, Fort Collins’ Canyon Concert Ballet partnered with Animal Friends Alliance to showcase nine of the local rescue’s adoptable dogs and cats ahead of the ballet company’s annual production of “The Nutcracker.”

Like last year, Nutcracker dancers posed with the animals for photos celebrating both their upcoming shows and Animal Friends Alliance’s adoptable pets. Of the pets featured in the Nov. 20 photo shoot, all of the puppies have since been adopted. Gladys, a senior beagle involved in the shoot, is available for fostering and adoption this week, while the kittens featured will likely be available at an adoption event from 10 a.m. to 3 p.m. Saturday at PetSmart, 4432 S. College Ave, according to Animal Friends Alliance.

Here are the pictures – I wasn’t there, so I’m not sure of all the costume ID’s, but I am of most of them.

If I were that Rat King, I’d be terrified of that ferocious cat!

 

 

 

 

 

 

Sorry, sweetie, I gotta go dance the Trepak.

 

 

 

 

Looks like the dancers could just ear them all up…

 

 

 

 

 

I think this is one of the snowflakes … but the little sweeitie in her arms doesn’t appear to be chilled.

 

 

 

 

 

By the hair, and also the sleeves, I’m thinking this must be Clara.

 

 

 

The dances we usually think of as the Arabian Dance, Chinese Dance, and Spanish Dance are actually called “Coffee,” “Tea,” and “Chocolate,” in that order.  This looks like Chocolate to me.

 

 

 

 

 

 

Coffee being full of caffeine, it’s not surprising the dancers have the energy for four photos.  But I’ll only show two.

 

 

Here’s the second.

 

 

 

 

 

 

 

And I think this one is Tea.

 

 

 

 

 

 

 

 

Of course there has to be the Sugar Plum Fairy

 

 

 

 

 

Twice.

 

 

 

 

 

You can see all of the pictures (there are 17) if you click through on the headline – or here.  They’re shown as a “gallery” – see one, then click to the next and so on.  Virgil will be so proud of the town he grew up in for doing this.  They couldn’t have when he lived there – it was much smaller, although the university was already there.

I hope you enjoyed seeing this as much as I did.  A Happy Holiday season to all!

 

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